HDAC1/2 and CDK2-IN-1
HDAC1/2 and CDK2-IN-1 (compound 14d) is a dual-acting inhibitor targeting HDAC1, HDAC2, and CDK2 with IC50 values of 70.7, 23.1, and 0.80 μM, respectively. It induces cell cycle arrest and apoptosis, demonstrating anti-tumor efficacy in both cellular assays and in vivo models, making it a useful probe for oncology and epigenetics research.
Product Specifications
CAS Number
2418559-01-8
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Smiles
C (N1C=2C (=C (NC3=CC=C (C) C=C3) N=C (Cl) N2) N=C1) C4=CC=C (C (NC5=C (N) C=CC=C5) =O) C=C4
Molecular Formula
C26H22ClN7O
Molecular Weight
483.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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