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Everafenib

Everafenib is a brain-penetrant BRAF inhibitor that potently suppresses the MAPK pathway. It demonstrates superior in vitro potency against V600E BRAF melanoma cell lines compared to dabrafenib and vemurafenib and has shown efficacy in extending survival in intracranial melanoma mouse models.

Product Specifications

Field of Research

Signal Transduction

Molecular Formula

C20H23ClFN5O2S2

Molecular Weight

484.01

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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