Simmiparib
Simmiparib (SMOCL-9112) is an Olaparib-derived PARP1/2 inhibitor that induces DNA double-strand breaks and cell cycle arrest in HR-deficient cells, leading to apoptosis. It has been investigated in preclinical studies for cancers like breast cancer and melanoma, as well as in research models for neurodegenerative conditions including Parkinson's and Alzheimer's disease.
Product Specifications
CAS Number
1551355-46-4
Product Name Alternative
Apoptosis, PARP1, PARP2, SMOCL-9112
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Purity
99.05% (May vary between batches)
Solubility
DMSO:80 mg/mL (164.47 mM)
Smiles
CC1CN (Cc2nnc (n12) C (F) (F) F) C (=O) c1cc (Cc2n[nH]c (=O) c3ccccc23) ccc1F
Molecular Formula
C23H18F4N6O2
Molecular Weight
486.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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