RET-IN-6
RET-IN-6 is a highly potent and selective small molecule inhibitor of the RET kinase, demonstrating an IC50 of 4.57 nM. This compound is a valuable chemical probe for investigating RET-driven pathologies, such as certain cancers, in both cellular (in vitro) and animal model (in vivo) research studies.
Product Specifications
CAS Number
2715208-83-4
Field of Research
Cell Biology, Signal Transduction
Smiles
CN1C=C (C=2N=C (C3=C (C2) N=CC=C3) C=4C=CC (=NC4) N5CC6N (CC7=CC=CC=C7) C (C5) CC6) C=N1
Molecular Formula
C30H29N7
Molecular Weight
487.6
Storage Conditions
-20°C
Notes
For research use only.
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