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RET-IN-6

RET-IN-6 is a highly potent and selective small molecule inhibitor of the RET kinase, demonstrating an IC50 of 4.57 nM. This compound is a valuable chemical probe for investigating RET-driven pathologies, such as certain cancers, in both cellular (in vitro) and animal model (in vivo) research studies.

Product Specifications

CAS Number

2715208-83-4

Field of Research

Cell Biology, Signal Transduction

Smiles

CN1C=C (C=2N=C (C3=C (C2) N=CC=C3) C=4C=CC (=NC4) N5CC6N (CC7=CC=CC=C7) C (C5) CC6) C=N1

Molecular Formula

C30H29N7

Molecular Weight

487.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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