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P-gp/BCRP-IN-1

P-gp/BCRP-IN-1 is an orally bioavailable, dual inhibitor of the P-glycoprotein and BCRP efflux transporters. It is utilized in pharmacological research to overcome multidrug resistance and improve the oral absorption of co-administered substrates like paclitaxel, as demonstrated in preclinical models.

Product Specifications

CAS Number

2764596-06-5

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery

Smiles

C (NC1=CC=C (CCN2CCOCC2) C=C1) (=O) C=3C=4C (C (=O) N (N3) C5=CC=C (Cl) C=C5) =CC=CC4

Molecular Formula

C27H25ClN4O3

Molecular Weight

488.97

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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