P-gp/BCRP-IN-1
P-gp/BCRP-IN-1 is an orally bioavailable, dual inhibitor of the P-glycoprotein and BCRP efflux transporters. It is utilized in pharmacological research to overcome multidrug resistance and improve the oral absorption of co-administered substrates like paclitaxel, as demonstrated in preclinical models.
Product Specifications
CAS Number
2764596-06-5
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
C (NC1=CC=C (CCN2CCOCC2) C=C1) (=O) C=3C=4C (C (=O) N (N3) C5=CC=C (Cl) C=C5) =CC=CC4
Molecular Formula
C27H25ClN4O3
Molecular Weight
488.97
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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