BCR-ABL-IN-5

BCR-ABL-IN-5 is a potent inhibitor of both wild-type and T315I mutant Bcr-Abl kinase, with respective IC50 values of 0.014 μM and 0.45 μM. It demonstrates anti-proliferative activity in leukemic cell studies and serves as a valuable research tool for investigating chronic myeloid leukemia (CML) resistance mechanisms in vitro.