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Uplarafenib

Uplarafenib (B-Raf IN 10) is a potent and selective BRAF inhibitor with an IC50 of 50-100 nM. It demonstrates antitumor activity by inhibiting proliferation in vitro and has shown efficacy in vivo models of solid tumors, such as melanoma, supporting its use in oncology research.

Product Specifications

CAS Number

1425485-87-5

Product Name Alternative

B-Raf, B-Raf IN 10, Uplarafenib

Field of Research

Signal Transduction

Purity

99.85% (May vary between batches)

Solubility

DMSO:90 mg/mL (182.01 mM)

Smiles

CCCS (=O) (=O) Nc1cc (F) c (F) c (C (=O) c2ccc3ncc (nc3c2) N2CCOCC2) c1F

Molecular Formula

C22H21F3N4O4S

Molecular Weight

494.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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