Uplarafenib
Uplarafenib (B-Raf IN 10) is a potent and selective BRAF inhibitor with an IC50 of 50-100 nM. It demonstrates antitumor activity by inhibiting proliferation in vitro and has shown efficacy in vivo models of solid tumors, such as melanoma, supporting its use in oncology research.
Product Specifications
CAS Number
1425485-87-5
Product Name Alternative
B-Raf, B-Raf IN 10, Uplarafenib
Field of Research
Signal Transduction
Purity
99.85% (May vary between batches)
Solubility
DMSO:90 mg/mL (182.01 mM)
Smiles
CCCS (=O) (=O) Nc1cc (F) c (F) c (C (=O) c2ccc3ncc (nc3c2) N2CCOCC2) c1F
Molecular Formula
C22H21F3N4O4S
Molecular Weight
494.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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