Treprostinil diethanolamine
Treprostinil diethanolamine (UT-15C) is a potent EP2, DP1, and IP receptor agonist, with EC50 values in the nanomolar range. Its activation of these receptors elevates intracellular cAMP, promoting vasodilation, particularly in human pulmonary arteries, and supports vascular homeostasis. This mechanism underpins its research utility in studying pulmonary hypertension and vascular biology in both in vitro and in vivo models.
Product Specifications
CAS Number
830354-48-8
Product Name Alternative
Prostaglandin Receptor, ProstaglandinReceptor, UT-15C, Treprostinil diethanolamine, DP1, IP, EP2
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
98.21% (May vary between batches)
Solubility
DMSO:5.5 mg/mL (11.1 mM)
Smiles
N (CCO) CCO.C (C[C@H] (CCCCC) O) [C@@H]1[C@@]2 ([C@@] (CC=3C (C2) =CC=CC3OCC (O) =O) (C[C@H]1O) [H]) [H]
Molecular Formula
C27H45NO7
Molecular Weight
495.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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