HA2A/hCA XII modulator 1
This triazolopyrazine is a potent dual-target antagonist, selectively inhibiting the hA2A adenosine receptor (Ki: 6.4 nM) and human carbonic anhydrase XII (Ki: 6.2 nM) . Its dual activity makes it a valuable chemical probe for cancer research, particularly in studying tumor hypoxia and immunomodulation in relevant in vitro and in vivo models.
Product Specifications
CAS Number
2548963-55-7
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C1N2C (=NN1C3=CC=CC=C3) C (N) =NC (=C2) C4=CC=C (NC (=O) C5=CC=C (S (N) (=O) =O) C=C5) C=C4
Molecular Formula
C24H19N7O4S
Molecular Weight
501.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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