EGFR/HER2/TS-IN-1
EGFR/HER2/TS-IN-1 is a multi-targeted inhibitor active against EGFR, HER2, and thymidylate synthase with respective IC50 values of 0.203, 0.088, and 0.168 μM. It induces apoptosis in MCF7 breast cancer cells, making it a useful compound for in vitro studies in oncology research, particularly for investigating combination inhibition strategies.
Product Specifications
CAS Number
2444363-11-3
Field of Research
Cardiovascular Research, Cell Biology, Molecular Biology, Signal Transduction
Smiles
C (#N) C1=C (NC (SCC (NC2=NC=3C (S2) =CC (C) =CC3) =O) =NC1=O) C=4C (=O) C=5C (OC4) =CC=CC5
Molecular Formula
C24H15N5O4S2
Molecular Weight
501.54
Storage Conditions
-20°C
Notes
For research use only.
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