SMO-IN-2
SMO-IN-2 is a potent and selective smoothened (SMO) antagonist that inhibits the Hedgehog signaling pathway. It demonstrates antiproliferative and anticancer effects in human medulloblastoma cell lines in vitro and has been utilized in various in vivo cancer research models to study tumor growth and pathway inhibition.
Product Specifications
CAS Number
1822355-27-0
Product Name Alternative
Hedgehog, Smoothened
Field of Research
Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Purity
98.64% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.99 mM) ; DMSO:7.14 mg/mL (14.18 mM)
Smiles
N (C1=C (C (=O) N2CCC (N (C (=O) C3=C (C (F) (F) F) C=C (F) C=C3) C) CC2) C=CC=C1) C=4N (C) N=CC4
Molecular Formula
C25H25F4N5O2
Molecular Weight
503.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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