EGFR-IN-46
EGFR-IN-46 is a potent dual inhibitor targeting both EGFR (IC50 = 20.17 nM) and FAK (IC50 = 14.25 nM) . It demonstrates robust anti-proliferative and pro-apoptotic activity in cancer cell lines, making it a valuable chemical probe for researching oncogenic signaling pathways in vitro.
Product Specifications
CAS Number
2764772-88-3
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O (CCCNC1CCN (C) CC1) C=2C3=C (N=C (C2) C4=CC=C (C (F) (F) F) C=C4) C=C (OC) C (OC) =C3
Molecular Formula
C27H32F3N3O3
Molecular Weight
503.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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