Fluorescein

Fluorescein (Uranine) is widely used as a fluorescent tracer in medicinal and biological applications and tumor infected tissues tracer. Fluorescein (Uranine) is a representative green fluorophore that has been widely used as a scaffold of practically useful green fluorescent probes[1][2].

Product Specifications

CAS Number

[2321-07-5]

Product Name Alternative

Uranine

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Fluorescein.html

Purity

98.47

Solubility

DMSO : 83.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

O=C1OC2(C3=C(OC4=C2C=CC(O)=C4)C=C(O)C=C3)C5=C1C=CC=C5

Molecular Formula

C20H12O5

Molecular Weight

332.31

Precautions

H302, H315, H319, H335

References & Citations

[1]RobertSjöback, et al. Absorption and fluorescence properties of fluorescein. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy|[2]Nabel A Negm, et al. Fluorescein dye derivatives and their nanohybrids: Synthesis, characterization and antimicrobial activity. J Photochem Photobiol B. 2016 Sep;162:421-433.|[3]Li Liu, et al. Fluorescein as an artificial enzyme to mimic peroxidase. Chem Commun (Camb) . 2016 Nov24;52 (96) :13912-13915.|[4]Hirabayashi K, et al. Analysis of chemical equilibrium of silicon-substituted fluorescein and its application to develop a scaffold for red fluorescent probes. Anal Chem. 2015;87 (17) :9061-9069.