BCR-ABL-IN-6
BCR-ABL-IN-6 (9h) is a potent and selective imatinib-derived Bcr-Abl kinase inhibitor, active against both wild-type (IC50 = 4.6 nM) and the T315I mutant (IC50 = 277 nM) . This compound is a valuable research tool for investigating chronic myeloid leukemia (CML) in biochemical and cellular assays.
Product Specifications
CAS Number
2499499-26-0
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
C (F) (F) (F) C1=C (C=CC (C (NC2=CC (C#CC3=C4C (NN=C4N) =CC=C3) =CC=C2) =O) =C1) N5CCOCC5
Molecular Formula
C27H22F3N5O2
Molecular Weight
505.49
Storage Conditions
-20°C
Notes
For research use only.
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