PARP1/BRD4-IN-1
PARP1/BRD4-IN-1 is a potent dual inhibitor of PARP1 (IC50=49 nM) and BRD4 (IC50=202 nM) . It suppresses their expression and activity, demonstrating synergistic anti-proliferative effects in pancreatic cancer cell models in vitro, supporting its use in oncology research.
Product Specifications
CAS Number
2758117-74-5
Field of Research
Cell Biology, Epigenetics & Chromatin, Epigenetics & Chromatin; Cell Biology, Molecular Biology
Smiles
C (N1C (C=2C (N (C) C1=O) =CC=C (C2) C=3C (C) =NOC3C) C4=CC=CC=C4) C=5NC=6C (N5) =CC=CC6C (N) =O
Molecular Formula
C29H26N6O3
Molecular Weight
506.56
Storage Conditions
-20°C
Notes
For research use only.
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