HDAC1-IN-4
HDAC1-IN-4 is a potent and selective inhibitor of Plasmodium falciparum histone deacetylase 1 (PfHDAC1), exhibiting potent antimalarial activity with an IC50 below 5 nM. This compound demonstrates low cytotoxicity and is a valuable chemical probe for investigating epigenetic mechanisms in malaria parasite biology, supporting both in vitro and in vivo antimalarial research.
Product Specifications
CAS Number
2482998-39-8
Field of Research
Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology
Smiles
Cl.Cn1cc (CN2CC3 (C2) CCN (C3) c2ncc (cn2) C (=O) NO) c2ccc (Br) cc12
Molecular Formula
C21H24BrClN6O2
Molecular Weight
507.82
Storage Conditions
-20°C
Notes
For research use only.
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