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HDAC1-IN-4

HDAC1-IN-4 is a potent and selective inhibitor of Plasmodium falciparum histone deacetylase 1 (PfHDAC1), exhibiting potent antimalarial activity with an IC50 below 5 nM. This compound demonstrates low cytotoxicity and is a valuable chemical probe for investigating epigenetic mechanisms in malaria parasite biology, supporting both in vitro and in vivo antimalarial research.

Product Specifications

CAS Number

2482998-39-8

Field of Research

Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology

Smiles

Cl.Cn1cc (CN2CC3 (C2) CCN (C3) c2ncc (cn2) C (=O) NO) c2ccc (Br) cc12

Molecular Formula

C21H24BrClN6O2

Molecular Weight

507.82

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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