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OM-153

OM-153 is a potent dual inhibitor of tankyrase 1 and 2 (IC50 = 13 nM and 2 nM, respectively) . It suppresses WNT/β-catenin signaling and cellular proliferation, making it a valuable chemical probe for studying Wnt-driven cancers in both in vitro and in vivo research models.

Product Specifications

CAS Number

2406278-81-5

Field of Research

Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology

Smiles

CCOc1ccc (nc1) -c1nnc ([C@H]2C[C@@H] (C2) NC (=O) c2cccc3nccnc23) n1-c1ccccc1F

Molecular Formula

C28H24FN7O2

Molecular Weight

509.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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