OM-153
OM-153 is a potent dual inhibitor of tankyrase 1 and 2 (IC50 = 13 nM and 2 nM, respectively) . It suppresses WNT/β-catenin signaling and cellular proliferation, making it a valuable chemical probe for studying Wnt-driven cancers in both in vitro and in vivo research models.
Product Specifications
CAS Number
2406278-81-5
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
CCOc1ccc (nc1) -c1nnc ([C@H]2C[C@@H] (C2) NC (=O) c2cccc3nccnc23) n1-c1ccccc1F
Molecular Formula
C28H24FN7O2
Molecular Weight
509.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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