HDAC/Top-IN-1
HDAC/Top-IN-1 is an orally bioavailable, dual-action inhibitor targeting histone deacetylases (HDAC1, 2, 3, 6, 8) and topoisomerase. It induces S-phase arrest and apoptosis in cultured cancer cells like HEL cells, making it a valuable chemical probe for oncology research in both cellular and animal models.
Product Specifications
CAS Number
2411379-14-9
Field of Research
Epigenetics & Chromatin, Molecular Biology
Smiles
CN1C2 (C3=C (C=4C (N3) =CC=C (OCC5=CC=C (/C=C/C (NO) =O) C=C5) C4) CCN2C (=O) C=6C1=CC=C (F) C6) [H]
Molecular Formula
C29H25FN4O4
Molecular Weight
512.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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