HPK1-IN-28

HPK1-IN-28 is a potent small molecule inhibitor targeting Hematopoietic Progenitor Kinase 1 (HPK1), a key negative regulator of immune cell activation. It enhances anti-tumor immunity by potentiating dendritic, T-cell, and B-cell responses, showing research promise in immuno-oncology for both in vitro mechanistic studies and in vivo tumor models.