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ATR-IN-18

ATR-IN-18 is a potent and orally bioavailable ATR kinase inhibitor with an IC50 of 0.69 nM. It demonstrates anti-proliferative activity in LoVo colorectal cancer cells (IC50: 37.34 nM) and has shown promising anti-tumor efficacy in research models, supporting its investigation in oncology and DNA damage response studies.

Product Specifications

CAS Number

2766407-55-8

Field of Research

Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Smiles

OC (=O) C (F) (F) F.C[C@@H]1COCCN1c1nc2n (ncc2c2N (CCc12) S (C) (=O) =O) -c1cc[nH]n1

Molecular Formula

C19H22F3N7O5S

Molecular Weight

517.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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