ATR-IN-18
ATR-IN-18 is a potent and orally bioavailable ATR kinase inhibitor with an IC50 of 0.69 nM. It demonstrates anti-proliferative activity in LoVo colorectal cancer cells (IC50: 37.34 nM) and has shown promising anti-tumor efficacy in research models, supporting its investigation in oncology and DNA damage response studies.
Product Specifications
CAS Number
2766407-55-8
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Smiles
OC (=O) C (F) (F) F.C[C@@H]1COCCN1c1nc2n (ncc2c2N (CCc12) S (C) (=O) =O) -c1cc[nH]n1
Molecular Formula
C19H22F3N7O5S
Molecular Weight
517.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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