RF9 hydrochloride

RF9 hydrochloride is a potent and selective antagonist of human Neuropeptide FF receptors, demonstrating high affinity for hNPFF2R (Ki: 7 nM) and hNPFF1R (Ki: 58 nM) . This small molecule is a valuable research tool for investigating the NPFF system's role in pain modulation, opioid tolerance, and reward pathways in both in vitro and in vivo studies.