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USP1-IN-3

USP1-IN-3 is a potent and selective small molecule inhibitor of the USP1-UAF1 deubiquitinase complex, with an IC50 below 30 nM. This compound is a valuable research tool for investigating DNA damage response pathways and has been utilized in both cellular and animal models to study oncology and cancer therapeutics.

Product Specifications

CAS Number

2821749-58-8

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry

Smiles

O (C) C1=C (C (=NC=N1) C2CC2) C=3N=C4C (CC5=CC=C (C=C5) C6=NC (C (F) (F) F) =CN6C) =CN (C) C4=CN3

Molecular Formula

C27H24F3N7O

Molecular Weight

519.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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