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Exarafenib

Exarafenib (RAF/KIN_2787) is an orally bioavailable, pan-RAF inhibitor that suppresses the MAPK signaling pathway, demonstrating antitumor efficacy. It is utilized in cancer research for investigating RAF-driven malignancies in both cellular and animal models.

Product Specifications

CAS Number

2639957-39-2

Product Name Alternative

Exarafenib, p38MAPK, p38 MAPK, RAF/KIN_2787

Field of Research

Signal Transduction

Purity

98.36% (May vary between batches)

Solubility

DMSO:50 mg/mL (95.86 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.83 mM)

Smiles

C[C@H] (CO) Nc1cc (cc (n1) N1CCOCC1) -c1cc (NC (=O) N2CC[C@@H] (CC (F) (F) F) C2) ccc1C

Molecular Formula

C26H34F3N5O3

Molecular Weight

521.58

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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