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HPK1-IN-10

HPK1-IN-10 is a potent and selective small molecule inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1/MAP4K1), a key negative regulator of T-cell signaling. This compound is a valuable research tool for investigating HPK1 biology in immuno-oncology, enabling mechanistic studies in both cellular assays and in vivo disease models.

Product Specifications

CAS Number

2734168-69-3

Field of Research

Signal Transduction

Smiles

C (=O) (C1=CC=C (C=2C=3C (NC2) =NC=C (C3) C=4C=C5C (=CC4) N6C (CO5) CN (C) CC6) C=C1) N7CC (N (C) C) C7

Molecular Formula

C31H34N6O2

Molecular Weight

522.64

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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