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DC-U4106

DC-U4106 is a small molecule inhibitor targeting USP8 (Kd: 4.7 μM) that induces the degradation of estrogen receptor alpha (ERα) via the ubiquitin-proteasome pathway. It demonstrates potent anti-proliferative activity in breast cancer cell models with low cytotoxicity, supporting its use for in vitro and in vivo research into ER-positive cancers.

Product Specifications

CAS Number

2410534-62-0

Field of Research

Cell Biology, Molecular Biology, Protein Biochemistry

Smiles

Cc1n[nH]c (C) c1Oc1c (O) cc (O) c2c1oc (cc2=O) -c1ccc (cc1) N1CCN (CC1) c1ccccn1

Molecular Formula

C29H27N5O5

Molecular Weight

525.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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