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Vamotinib

Vamotinib (PF-114) is a specific, orally bioavailable tyrosine kinase inhibitor that potently targets both native and T315I-mutant BCR-ABL, inducing apoptosis. It is a valuable research tool for investigating drug-resistant Ph+ leukemias and has been explored in preclinical models of Alzheimer's disease.

Product Specifications

CAS Number

1416241-23-0

Product Name Alternative

Bcr-Abl, BcrAbl, Apoptosis, PF-114, Tyrosine Kinases, TyrosineKinases

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Purity

99.34% (May vary between batches)

Solubility

10% DMSO+90% Saline:2 mg/mL (3.76 mM) ; DMSO:30 mg/mL (56.33 mM)

Smiles

CN1CCN (Cc2ccc (NC (=O) c3ccc (C) c (c3) C#Cc3nnc4ccccn34) cc2C (F) (F) F) CC1

Molecular Formula

C29H27F3N6O

Molecular Weight

532.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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