G12Si-1
G12Si-1 is a selective, covalent inhibitor of the K-Ras (G12S) oncoprotein. It effectively disrupts oncogenic signaling by binding the mutant serine residue and can impede nucleotide exchange processes. This inhibitor is a valuable tool for investigating K-Ras-driven cancers in both cellular and biochemical studies.
Product Specifications
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C29H32ClN5O3
Molecular Weight
534.05
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TRC-T888000-2.5MG 2.5 mg
(3Beta,5Beta,7Alpha,12Alpha)-3,7,12-Trihydroxy-cholestan-26-oic Acid
Sign In for Pricing
View Details 
BNC472600-500 1x 500 µL
EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNUB2309-100 1x 100 µL
NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/1523), 0.2mg/mL
Sign In for Pricing
View Details 