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G12Si-1

G12Si-1 is a selective, covalent inhibitor of the K-Ras (G12S) oncoprotein. It effectively disrupts oncogenic signaling by binding the mutant serine residue and can impede nucleotide exchange processes. This inhibitor is a valuable tool for investigating K-Ras-driven cancers in both cellular and biochemical studies.

Product Specifications

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Molecular Formula

C29H32ClN5O3

Molecular Weight

534.05

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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