ACT-660602
ACT-660602 is a potent and orally bioavailable CXCR3 antagonist (IC50 = 204 nM) that suppresses T cell migration. It has demonstrated efficacy in an acute lung injury model and serves as a valuable research tool for investigating autoimmune disease mechanisms in both in vitro and in vivo settings.
Product Specifications
CAS Number
1646267-59-5
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
C[C@@H]1CN (CCN1C (=O) Cn1nc (C) nc1C) c1sc (nc1-c1cnc (nc1) C (F) (F) F) C (F) (F) F
Molecular Formula
C20H20F6N8OS
Molecular Weight
534.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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