RET-IN-5
RET-IN-5 is a highly potent and selective small molecule inhibitor of the RET kinase, demonstrating an IC50 value of 4.57 nM. It is a valuable research tool for investigating RET-driven pathologies, such as certain cancers, in both cellular and animal model studies.
Product Specifications
CAS Number
2725770-20-5
Field of Research
Cell Biology, Signal Transduction
Smiles
C (#N) C1=C2C (=CC (OCC (C#N) (C) C) =CN2N=C1) C=3C=CC (N ([C@@H] (C) C=4C=CC (=NC4) N5C=C (F) C=N5) C) =NC3
Molecular Formula
C29H26FN9O
Molecular Weight
535.57
Storage Conditions
-20°C
Notes
For research use only.
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