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PND-1186 hydrochloride

PND-1186 hydrochloride (VS-4718) is a potent, reversible, and selective FAK inhibitor with an IC50 of 1.5 nM. It is widely used in cancer research to study FAK's role in tumor cell survival, proliferation, and metastasis, demonstrating pro-apoptotic effects in both in vitro and in vivo models.

Product Specifications

CAS Number

1356154-94-3

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

Cl.CNC (=O) c1ccccc1Nc1cc (Nc2ccc (cc2OC) N2CCOCC2) ncc1C (F) (F) F

Molecular Formula

C25H27ClF3N5O3

Molecular Weight

537.97

Storage Conditions

-20°C

Notes

For research use only.

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