K20
K20 is a potent and selective KRas G12C inhibitor (IC50: 1.16 nM) demonstrating in vitro anticancer activity in H358 cells (IC50: 0.78 μM) and in vivo tumor growth inhibition (TGI: 41%) . It induces apoptosis by reducing Erk phosphorylation, making it a valuable tool for oncology and signal transduction research.
Product Specifications
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C24H20Cl2F4N4O2
Molecular Weight
543.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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