LRRK2-IN-2
LRRK2-IN-2 is a potent, selective, and brain-penetrant inhibitor of LRRK2 kinase, exhibiting an IC50 of 0.6 nM. This orally bioavailable compound is a valuable research tool for investigating LRRK2's role in Parkinson's disease pathogenesis in both cellular and animal models.
Product Specifications
CAS Number
2641059-19-8
Field of Research
Cell Biology
Smiles
FC1 (F) [C@H] (C1) N2C (Cl) =C (NC3=NC4=C (C=N3) C=C (Cl) C (=C4) [C@H]5[C@H] (F) CN (CC5) [C@H]6[C@@H] (O) COC6) C=N2
Molecular Formula
C23H23Cl2F3N6O2
Molecular Weight
543.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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