RET-IN-19
RET-IN-19 is a potent small molecule RET inhibitor effective against both wild-type (IC50: 6.8 nM) and V804M mutant (IC50: 13.51 nM) forms. It is a valuable research tool for investigating RET-driven cancers, including non-small cell lung cancer (NSCLC), in both cellular and animal model studies.
Product Specifications
CAS Number
2484919-71-1
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction
Smiles
N (C1=C2C (NC (=C2) C3=CC=C (S (C) (=O) =O) C=C3) =NC=N1) C4=CC=C (CC (NC=5C=C (C (C) (C) C) ON5) =O) C=C4
Molecular Formula
C28H28N6O4S
Molecular Weight
544.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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