KRAS G12C inhibitor 47
This potent and selective KRAS G12C inhibitor (IC50: 0.172 μM) demonstrates strong p-ERK inhibition in cellular models like MIA PaCa-2 cells. It is a valuable research tool for investigating targeted therapies in pancreatic, colorectal, and non-small cell lung cancers, supporting both in vitro and in vivo oncology studies.
Product Specifications
CAS Number
2253119-24-1
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C1N (C=2C (C (=N1) N3CCN (C (C=C) =O) CC3) =CC (Cl) =C (C2) C4=C (F) C=CC=C4O) C5=C (C (C) C) C=CC=C5
Molecular Formula
C30H28ClFN4O3
Molecular Weight
547.02
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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