Bosutinib hydrate
Bosutinib hydrate (SKI-606 hydrate) is an orally bioavailable, dual inhibitor targeting BCR-ABL and Src tyrosine kinases. It is a research compound used in preclinical studies for Philadelphia chromosome-positive leukemias, demonstrating activity in both cellular assays and animal models of chronic myeloid leukemia.
Product Specifications
CAS Number
918639-08-4
Product Name Alternative
Bcr-Abl, BcrAbl, Src, SKI-606 hydrate, PF-05208763 hydrate, PF-5208763 hydrate
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.87% (May vary between batches)
Solubility
DMSO:80 mg/mL (145.86 mM)
Smiles
O.COc1cc (Nc2c (cnc3cc (OCCCN4CCN (C) CC4) c (OC) cc23) C#N) c (Cl) cc1Cl
Molecular Formula
C26H31Cl2N5O4
Molecular Weight
548.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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