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TRβ agonist 1

TRβ Agonist 1 is a potent and selective thyroid hormone receptor β agonist with an EC50 of 21 nM, demonstrating sensitivity to specific mutations. It serves as a valuable research tool for studying dyslipidemia, NASH, and resistance to thyroid hormone (RTH), with applications in both cellular and animal models of metabolic disease.

Product Specifications

CAS Number

2770681-85-9

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

O (C) C=1C2=C (C (O) =C (C (NCC (O) =O) =O) N1) C=CC (OC3=C (C) C=C (C (=O) C4=CC (OC) =CC (F) =C4) C=C3C) =C2

Molecular Formula

C29H25FN2O8

Molecular Weight

548.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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