KRAS G12C inhibitor 50
This small molecule compound is a potent and selective inhibitor of the KRAS G12C mutant protein, exhibiting an IC50 of 46.7 nM. It is a valuable research tool for investigating targeted cancer therapies in both in vitro biochemical assays and in vivo preclinical models of KRAS G12C-driven cancers.
Product Specifications
CAS Number
2760354-12-7
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (C=1N2C (C (=NC (OC[C@@H]3CCCN3C) =N2) N4C[C@H] (CC#N) N (C (C=C) =O) CC4) =NC1) C=5C6=C (C=CC5) C=CC=C6
Molecular Formula
C31H34N8O2
Molecular Weight
550.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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