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PDE5/HDAC-IN-1

PDE5/HDAC-IN-1 is a dual-targeting small molecule that potently inhibits phosphodiesterase 5 (IC50=46.3 nM) and histone deacetylase (IC50=14.5 nM) . This compound is a valuable research tool for investigating related pathways in oncology and cardiovascular disease models, both in cellular and biochemical assays.

Product Specifications

CAS Number

2414921-48-3

Field of Research

Cell Biology, Epigenetics & Chromatin, Metabolism Research, Molecular Biology

Smiles

O=C1N2[C@@H] (C3=C (C=4C (N3) =CC=CC4) C[C@@]2 (C (=O) N (CCCCCCC (NO) =O) C1) [H]) C5=CC=C (Br) C=C5

Molecular Formula

C27H29BrN4O4

Molecular Weight

553.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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