IKKβ-IN-1
IKKβ-IN-1 is a potent and orally bioavailable inhibitor of IKK-β (IC50 = 0.20 μM) . It suppresses PGE2 and TNF-α production in murine macrophage models and has demonstrated protective efficacy in mouse models of septic shock, highlighting its utility for inflammation and immunology research.
Product Specifications
CAS Number
2410423-31-1
Field of Research
Signal Transduction
Smiles
O=C\1N (C (=O) S/C1=C\C2=CC=C (OC3=CC=C (C#N) C=C3) C=C2) C4=CC=C (OCCCN5CCN (C) CC5) C=C4
Molecular Formula
C31H30N4O4S
Molecular Weight
554.66
Storage Conditions
-20°C
Notes
For research use only.
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