LSD1-IN-19

LSD1-IN-19 is a potent and selective non-covalent inhibitor of LSD1, demonstrating a Ki of 0.108 μM and a KD of 0.068 μM. It shows cellular activity with 72-hour IC50 values of 0.17 and 0.40 μM, making it a useful chemical probe for epigenetic research in oncology, both in vitro and in vivo.