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EGFR-IN-50

EGFR-IN-50 is a potent small molecule inhibitor targeting EGFR resistance mutations, including L858R and T790M/L858R, with GI50 values of 8 nM and 6.03 μM in respective BaF3 cell models. It is a valuable research tool for studying non-small cell lung cancer (NSCLC) resistance mechanisms and evaluating anti-proliferative effects in vitro.

Product Specifications

CAS Number

2044508-48-5

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

N (C=1C2=C (C=C (OCCCOC (CCSSCC=C) =O) C (OC) =C2) N=CN1) C3=CC (Br) =CC=C3

Molecular Formula

C24H26BrN3O4S2

Molecular Weight

564.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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