EGFR-IN-50
EGFR-IN-50 is a potent small molecule inhibitor targeting EGFR resistance mutations, including L858R and T790M/L858R, with GI50 values of 8 nM and 6.03 μM in respective BaF3 cell models. It is a valuable research tool for studying non-small cell lung cancer (NSCLC) resistance mechanisms and evaluating anti-proliferative effects in vitro.
Product Specifications
CAS Number
2044508-48-5
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
N (C=1C2=C (C=C (OCCCOC (CCSSCC=C) =O) C (OC) =C2) N=CN1) C3=CC (Br) =CC=C3
Molecular Formula
C24H26BrN3O4S2
Molecular Weight
564.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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