Thi-DPPY
Thi-DPPY is a potent and orally active dual inhibitor of JAK3 (IC50: 1.38 nM) and BTK (IC50: 62.4 nM) . It demonstrates anti-proliferative effects in HBE cells in vitro and exhibits anti-inflammatory activity in vivo, showing research potential for idiopathic pulmonary fibrosis (IPF) and related inflammatory disease models.
Product Specifications
CAS Number
2307699-34-7
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O (C1=C2C (=NC (NC3=CC (Cl) =C (OCCCN4CCOCC4) C=C3) =N1) C=CS2) C5=CC (NC (C=C) =O) =CC=C5
Molecular Formula
C28H28ClN5O4S
Molecular Weight
566.07
Storage Conditions
-20°C
Notes
For research use only.
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