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RORγt agonist 3

RORγt agonist 3 is a potent small molecule that activates RORγt to drive Th17 cell differentiation and enhance pro-inflammatory cytokine production, thereby increasing lymphocyte cytotoxicity while inhibiting regulatory T cell generation. This compound is a valuable research tool for studying Th17/IL-17 pathways, Treg/Th17 balance, and autoimmune disease mechanisms in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2664106-24-3

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

N (CC1CC1) (C2=CC (=CC (=C2) C3CC3) C4CC4) C5=CC=C (C (N[C@@H] (CC#N) C6=CC=C (S (CC) (=O) =O) C=C6) =O) C=C5

Molecular Formula

C34H37N3O3S

Molecular Weight

567.74

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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